SOX2 and major depressive disorder: Interestingly, the decreased levels of Sox2, the laminin 67 kDa protein, and tubulin beta-III without modifications of MASH1 in hNPCs-OE in MDD suggest that hNPCs-OE stayed in a multipotent stage with the capability to form not only neurons but also astrocytes (personal communication Dr. Adan Hernández-Cortés, Instituto de Neurobiología, UNAM).