Both ion channel and non-ion channel variants have been found to be linked to AF.31 Among the ion channel variants associated with AF, Feghaly et al. have described several potassium channels, including KCNQ1, KCNH2, and KCND3, as well as sodium channels such as SCN5A, SCN1B, and SCN2B. The gene discussed is SCN2B; the disease is atrial fibrillation.