We conducted a comprehensive validation of gene expression and observed that the oncogenesis of ovarian cancer is intricately linked to the downregulation of MAF, ZNF532, SCN2A, BCL2, and ELAVL2.Moreover, after the selection of specific genes, a comprehensive survival analysis is conducted to ascertain their prognostic significance in relation to overall survival. The gene discussed is SCN2A; the disease is ovarian cancer.