TCF4 and neoplasm: We also examined AMD1 expression, TCF4 expression and eIF5A hypusination level in tumor samples from mouse model by Western blotting, showing that consistent with the analysis of cell lines, these tumor samples with knockdown of AMD1 expression had a dramatic decrease in AMD1 expression, TCF4 expression and eIF5A hypusination (Fig. 7E), indicating similar effects in vitro and in vivo.