MYC and neoplasm: The results revealed that the gene sets of the high-risk samples were gathered in pathways related to mitotic spindle, myc targets, G2M checkpoint, DNA repaire, UV response and mtorc1 signaling, while the low-risk group were enriched in fatty acid metabolism, myogenesis and bile acid metabolism, suggesting that there was a significant difference in tumor growth, metabolism, metastasis and therapy response (Fig. 4C).