Based on the findings in this study, we proposed a working model: tumor-suppressive miR-4732-3p inhibits NSCLC progression by targeting MFSD12 to downregulate AKT signaling, which leads to p21-mediated G2/M cell cycle arrest; NSCLC cells avoid suppressive effects of miR-4732-3p through hnRNPK-mediated sorting of miR-4732-3p into fucosylated exosomes (Fig. 7C). Here, HNRNPK is linked to neoplasm.