The KEGG enrichment analysis identified pathways more significantly enriched in the high-risk group, including the IL-17 signaling pathway, Hippo signaling pathway, Wnt signaling pathway, TNF signaling pathway, hematopoietic cell lineage, estrogen signaling pathway, proteoglycans in cancer, PI3K-Akt signaling pathway, pathways in cancer, and NOD-like receptor signaling pathway, as shown in Fig. 7D-E. Here, TNF is linked to cancer.