Our recent study found that the expression of HIF−1α in the intestinal mucosa of rats with sepsis was upregulated and that the administration of the HIF−1α activator dimethyloxallyl glycine (DMOG) inhibited sepsis-induced inflammatory responses and oxidative stress levels, increased antioxidant levels, and alleviated intestinal mucosal barrier injury. Here, HIF1A is linked to Sepsis.