CCNF and nonpapillary renal cell carcinoma: In the TCGA cohort (Table 2), ccRCC patients affected by advanced T and TNM stage (both p < 0.0001), or those with a proven positive lymph node (p = 0.014), or M1 disease (p < 0.0001) more frequently had tumors with CCNF-high expression than CCNF-low expression.