CDKN1B and primary cutaneous T-cell non-Hodgkin lymphoma: To further understand how KPT-330 modulated p53, p21WAF1/Cip1, p27Kip1, and survivin protein expression levels in CTCL cells, we checked the transcript levels of these target proteins in cells treated with KPT-330 (250 nM) for 48 h.