Genome-wide association studies (GWAS) of neuroblastoma have identified over a dozen susceptibility loci and these genetic associations have implicated genes such as CASC15, NBAT1, BARD1, LMO1, DUSP12, DDX4, IL31RA, HSD17B12, HACE1, LIN28B, TP53, RSRC1, MLF1, CPZ, MMP20, KIF15, and NBPF2328–37. Here, DDX4 is linked to neuroblastoma.