It is associated with increased longevity, functional capacity, improved cognitive functions, and reduced dementia.6, 7, 8, 9, 10, 11Experts in cognitive aging point out the need to stimulate neuroplasticity through the learning process, in addition to the positive effect of physical exercise due to the greater expression of neurotrophins such as the BDNF.12The combined interventions of physical exercises with cognitive stimulation performed in sedentary posture or activities requiring the use of technology (such as exergames) can improve cognitive functions.13, 14, 15, 16, 17. This evidence concerns the gene BDNF and dementia.