In total, we annotated 11 factors: cell-cycle-1, cell-cycle-2, NPC-late, NPC-OPC-late, NPC-OPC-early, OPC-early, OPC, MES-early, MES-1, MES-2, MES-late, and MES-AC (Figure S1B; Figures 1C–1E); the top-ranked genes of cell-cycle-1 and cell-cycle-2 were combined into a single cell cycle factor. This evidence concerns the gene NPC1 and nasopharyngeal carcinoma.