Median abundance of cytotoxic lymphocytes, CD8+ T cells, NK cells, myeloid dendritic cells, and endothelial cells was highest in ccRCC, while B lineage, fibroblasts, neutrophils, and monocytic lineage abundance was highest in collecting duct, medullary, papillary, and mixed RCC subtypes, respectively (Figure 4B). The gene discussed is CD8A; the disease is nonpapillary renal cell carcinoma.