Cell cycle (mean Z score, 0.78 vs. –0.03 in ccRCC; P < 0.05) and fatty acid synthesis (FAS)/pentose phosphate scores (mean Z score, 0.97 vs. –0.14 in ccRCC; P < 0.001) were significantly increased in collecting duct carcinoma. This evidence concerns the gene FAS and collecting duct carcinoma.