Platelet activation in the ex vivo functional assay was positively associated with PF4/P IgG levels in patient plasma (Rs = 0.293, P = 0.035; Figure 4C) and trended in the direction of a negative correlation with the associated peripheral platelet count observed in the patients with malaria (Rs = –0.243, P = 0.09; Figure 4D). The gene discussed is PF4; the disease is malaria.