CD8A and cancer: Consistent with those observations, NLRC4 expression (which we found associated with DC2/DC3 subsets in cancer tumors) correlated strongly with CD4 expression (r = 0.69, P < 2.2 × 10–16) in COAD patient tumors, and CD8A to a lesser extent (r = 0.47, P < 2.2 × 10–16) (Figure 5B).