Therefore, to explore the mechanism by which Yap1 promotes ColVI deposition, we leveraged publicly available Tead1 ChIP-Seq data (Gene Expression Omnibus [GEO] GSE55186) from Yap1-driven embryonal rhabdomyosarcoma (eRMS) (39), skeletal muscle–derived tumors that lie on morphologic and transcriptional continua with UPS (40). This evidence concerns the gene YAP1 and embryonal rhabdomyosarcoma.