Although decreased expression of OTULIN protein is a common feature among ORAS patients (Damgaard et al., 2016, 2019; Zhou et al., 2016; Zinngrebe et al., 2022), the amount of OTULIN in the PBMCs and EBV-B cells from this patient was comparable with that in respective control cells (Fig. 2, A and B). The gene discussed is OTULIN; the disease is autoinflammation, panniculitis, and dermatosis syndrome, autosomal recessive.