CTTN and cancer: In particular, ATAT1 overexpression in a non-metastatic cancer cell line increases K40 tubulin acetylation and enhances the formation of microtentacles, membrane-based protrusions that aid cells in suspension to reattach to the substrate [105], while in a metastatic cancer cell line ATAT1 colocalizes and regulates cortactin acetylation levels, and this colocalization is required for the migratory and invasive capacities of these cells [27].