NFKB1 and cancer: Polymyxin VI (PPVI) uses the ROS/NF‐κB/NLRP3/GSDMD signalling axis to awaken caspase‐1 to complete the cleavage mission of GSDMD to promote pyroptosis in NSCLC cancer cells, demonstrating the potential of PPVI for inhibiting NSCLC progression.46