CD274 and neoplasm: A linear association of NS with tumor PD-L1 expression (Pearson r = 0.30; P = 0.03) and PD-L1/FKBP51s PB TAMs (Pearson r = 0.38; 0.05; Fig 4D; Supplementary Table S6) suggested that PD-L1–expressing tumors are more prone to necrosis.