TPO and autoimmune thrombocytopenic purpura: The risk factors for the development of thrombosis in ITP can be divided into three groups: related to the patient (classic risk factors such as immobility, surgery, cancer, tobacco...), related to the treatment (splenectomy, intravenous immunoglobulins [IVIG], corticosteroids, and TPO receptor agonists [TPO-RA]), and related to ITP.