Moreover, unstable or fluctuating sleep duration over time has been linked to increased risk of cardiovascular diseases and all-cause mortality [12,13,37], as well as elevated levels of inflammatory markers, such as C-reactive protein and interleukin-6 [10,11], which can contribute to many diseases, including coronary heart disease, stroke, and all-cause mortality [38,39]. This evidence concerns the gene IL6 and stroke disorder.