When comparing the sensitivity analysis and the first approach (Table 10), several factors maintained significance in both analyses: the time elapsed since the last vaccine dose or infection (CD8 + T cells against the BA.2 antigen), the number of SARS-CoV-2 vaccine doses received (CD8+ T cells against the Wuhan antigen) and anti-N IgM (CD8+ T cells against the BA.2 antigen). The gene discussed is CD40LG; the disease is infection.