AHR and malignant colon neoplasm: The AhR and AhR agonists also inhibited colon tumor formation in an inflammation model of colon cancer where mice are treated with the carcinogen azoxymethane (AOM) in combination with inflammatory stressor dextran sodium sulfate (DSS), and in a syngeneic mouse model using MC38 colon cancer cells injected into the right flank [22].