In the absence of probiotics, infection by V. coralliilyticus caused an increase in expression of the 26S proteasome non-ATPase regulatory subunit 10 protein (PSMD10) and serine/threonine-protein kinase RIO3 (RIOK3), both of which have been found to inhibit NF-kB activation (Figure 5). This evidence concerns the gene NFKB1 and infection.