This intricate involvement positions MCP1 as a key player in the pathogenesis of inflammatory diseases, including psoriasis, rheumatoid arthritis (88), and various neurological conditions such as brain ischemia (89), Alzheimer’s (90), experimental autoimmune encephalomyelitis (EAE) (91), and traumatic brain injury (92, 93). The gene discussed is CCL2; the disease is brain ischemia.