This intricate involvement positions MCP1 as a key player in the pathogenesis of inflammatory diseases, including psoriasis, rheumatoid arthritis (88), and various neurological conditions such as brain ischemia (89), Alzheimer’s (90), experimental autoimmune encephalomyelitis (EAE) (91), and traumatic brain injury (92, 93). This evidence concerns the gene CCL2 and rheumatoid arthritis.