T helper 2 (TH2) cells via production of interleukin-4 (IL-4) and subsequent IgE are responsible for IgE-mediated food allergies but have also been implicated in non-IgE-mediated food allergies by production of cytokines IL-3, IL-5, and IL-13 (6, 7). The gene discussed is IL4; the disease is food allergy.