CD4 and osteomyelitis: In the TBNK cell group, all immune features showed a positive causal relationship with the development of osteomyelitis: CD4+ AC (p = 0.016, OR = 1.163, 95%CI = 1.028–1.316); HLA DR+ CD4+ %T cell (p = 0.032, OR = 1.316, 95%CI = 1.023–1.692); HLA DR+ CD4+ %lymphocyte (p = 0.046, OR = 1.228, 95%CI = 1.003–1.504); HLA DR + CD8br AC (p = 0.010, OR = 1.146, 95%CI = 1.032–1.273); and CD3 on HLA DR + T cell (p = 0.025, OR = 1.184, 95%CI = 1.021–1.373).