MT-CO3 and Reduced sperm motility: A 2-fold decrease of expression of genes related to mitochondrial cytochrome oxidase subunits and asthenozoospermia was documented (mt-Co2, mt-Co3) (Fig. 7) (Baklouti-Gargouri et al., 2013; Heidari et al., 2016; Mostafa et al., 2016).