Therefore, in order to clarify whether the promotion of tumor growth by SUV39H1 is related to tumor angiogenesis, we studied the correlation between the expression of SUV39H1, Notch1 and CD31 proteins, and the results showed that the expression of SUV39H1 was significantly positively correlated with the expression of Notch1 and CD31 proteins. The gene discussed is NOTCH1; the disease is neoplasm.