After adjustment in the Model 3 for age, gender, race, poverty income ratio, education, smoking status, physical activity level, DM, hypertension, hyperlipidemia, ALT, AST, glycohemoglobin, TC, TG, HDL-c, SBP, DBP, probiotic and prebiotic supplements were an independent protective factor for HS (OR = 0.85, 95% CI: 0.73–0.99, p = 0.04). Here, GPT is linked to hyperlipidemia.