AK1 and acute myeloid leukemia: The other five significant prognostic genes with high AUCs were DGAT1, RPL3L, CSTB, AK1, and PRDX5. DGAT1 (DiacylGlycerol O-AcylTransferase 1) encodes a multipass transmembrane protein, which acts as a key metabolic enzyme and has been explored in a few cancers including AML by a few studies (He et al., 2021; Liu et al., 2022).