GATA3 is required for luminal epithelial cell differentiation in mammary gland,[25] and also drives the transition from pluripotency to differentiation in human embryonic stem cells.[26] FOXP3 serves as a tumor suppressor in breast cancer cells[27] and inhibits the tumor metastasis,[28] however, in non‐small cell lung cancer, FOXP3 promotes tumor growth and metastasis by activating Wnt/β‐catenin signaling pathway and epithelial–mesenchymal transition.[29]. The gene discussed is FOXP3; the disease is breast cancer.