The qRT-PCR findings demonstrated that the downregulation of ZNF692 in 143B and U2OS cells led to a decrease in the expression of TNK2, as seen in Fig. 5C. Conversely, the excessive production of ZNF692 in osteosarcoma cells resulted in an elevated expression of TNK2, as seen in Fig. 5D. In summary, our findings indicate that ZNF692 may have a favorable regulatory effect on TNK2. Here, TNK2 is linked to osteosarcoma.