Yet, compared to normal controls, the proportion of CD45RA- CD103-CD8 + KLRB(CD161) + GZMK + Mucosal-associated invariant T (MAIT) cells decreased in SLE patients (6.200 ± 1.103%, (N = 25) vs. 1.158 ± 0.2279%, (N = 38), p =  < 0.0001; MFI: 3709 ± 197.6 (N = 38) vs. 4323 ± 329.3 (N = 25), p = 0.9589). The gene discussed is CD8A; the disease is systemic lupus erythematosus.