Table 3 showed that the percentages of CD279 (8.027 ± 0.7983%, (N = 91) vs. 3.93 ± 0.7035%, (N = 27), p = 0.008) and TIGIT (25.67 ± 1.119%, (N = 90) vs. 20.13 ± 0.8377% (N = 26), p = 0.0109) expressions on CD4+ T cells were expanded in SLE patient. The gene discussed is PDCD1; the disease is systemic lupus erythematosus.