As shown in Table 4, CD8 + CD279 + TIM3 + (0.5922 ± 0.09517, (N = 90) vs. 0.08077 ± 0.01666, (N = 26), p = 0.0048) and CD8 + HLA-DR + CD38 + (13.75 ± 1.162 (N = 87), vs. 4.519 ± 0.8416 (N = 27), p < 0.0001) T cells were higher in patients with SLE. This evidence concerns the gene PDCD1 and systemic lupus erythematosus.