In contrast, CD127 expression on CD8 + T cells was reduced in SLE patients compared to HC (22.46 ± 1.752%, (N = 90) vs. 40.86 ± 4.19% (N = 27), p < 0.0001; MFI: 360.8 ± 7.882 vs. 421 ± 14.87, p = 0.0003). This evidence concerns the gene IL7R and systemic lupus erythematosus.