GZMK and systemic lupus erythematosus: Additionally, ESRD patients have a slightly higher quantity of CD45RA-CD8 + CD103-CD161 + GZMK + T MAIT cells than other SLE patients (2.070 ± 1.18 (N = 5) vs. 1.234 ± 0.2120 (N = 38)). Therefore, a diversity of GZMK + CD8 T cells may be responsible for an upsurge in GZMK expression in ESRD patients comparing to other SLE patients.