In contrast, CD127 expression on CD4 + T cells was reduced in SLE patients compared to HC (33.85 ± 2.343%, (N = 90) vs. 44.59 ± 5.149% (N = 27), p = 0.0382; MFI: 394.1 ± 6.585 vs. 421.3 ± 12.36, p = 0.0439). Here, CD4 is linked to systemic lupus erythematosus.