Quantitative PCR revealed nearly 4.5 fold-decrease of IL-10 and 1.5 fold-increase of IL-12p35 transcripts due to NLGP addition to tumor-conditioned cells, both of which were gradually counterbalanced by Laminarin, Dectin-1 siRNA and their combined inhibitory effects (Fig. 5a). Here, CLEC7A is linked to neoplasm.