Furthermore, the use of these cell types serves as a valuable in vitro model for assessing the effectiveness and feasibility of Aqp1 as a reporter transgene for future applications involving noninvasive and longitudinal tracking of biological functions in various animal models relevant to tumor biology, neuroscience, autoimmune disorders, and the development of gene- and cell-based therapies (Table S1). Here, AQP1 is linked to neoplasm.