CDK5R2 and hepatocellular carcinoma: The analysis of the heatmap showed that TRIM36, CYP26B1, PAGE1, CDK5R2, and DCAF8L1 had elevated expression levels in the high-risk score group among the HCC tissues of the TCGA training cohort (Fig. 7G), confirming their significant prognostic value in the TCGA training cohort.