Consistent with the results obtained for the training cohort and the test cohort, more deaths were reported among patients in the high-risk group, and the expression levels of CDK5R2, CYP26B1, DCAF8L1, PAGE1, and TRIM36 were notably higher in HCC tissues with high-risk scores (Fig. 10A). The gene discussed is CDK5R2; the disease is hepatocellular carcinoma.