Up-regulation of senescence markers such as p16ink4a and p21WAF1 has been disclosed in the lung epithelium of IPF patients together with bleomycin‐induced mouse pulmonary fibrosis models (Tian et al. 2019; Kuwano et al. 1996; Yanai et al. 2015). This evidence concerns the gene CDKN2A and idiopathic pulmonary fibrosis.