FOS and neoplasm: Overall, we identified 19 areas in NC26 tumor-bearing mice that showed statistically significantly (Padj < 0.1, two-sided unpaired t-tests with Benjamini–Hochberg multiple-testing correction with family-wise error rate (FWER) = 0.1) increased c-Fos expression compared to PBS controls after multiple-testing correction (Fig. 5a).