FOS and neoplasm: We found seven areas that were significantly altered between NC26 and cachectic C26 tumor-bearing mice, whereas we did not observe significant changes (Padj > 0.1, two-sided unpaired t-tests with Benjamini–Hochberg multiple-testing correction with FWER = 0.1) in c-Fos+ expression when comparing PBS and cachectic C26 tumor-bearing mice after correcting for multiple testing (Fig. 5a).