MKI67 and neoplasm: CEA (Fig. 7A6–C6 and Supplementary Fig. 1F) and CA19-9 (Fig. 7A7–C7 and Supplementary Fig. 1G) displayed weak positive expression, while Ki-67 (Fig. 7A3–C3 and Supplementary Fig. 1C) exhibited a 40% ratio, indicating rapid tumour proliferation.