Immunohistochemistry exhibited positive expression of CK7 (Fig. 7A1–C1 and Supplementary Fig. 1A), CK19 (Fig. 7A2–C2 and Supplementary Fig. 1B), E-cadherin (Fig. 7A4–C4 and Supplementary Fig. 1D) and Vimentin (Fig. 7A5–C5 and Supplementary Fig. 1E) in cell lines, transplanted tumours and primary tumours. This evidence concerns the gene VIM and neoplasm.