The distribution of Ago2, CAV1, endosome marker EEA1, and ER marker Calnexin (CANX) in normal lung epithelial cells BEAS-2B and lung cancer cells A549, A549Ago2-KO/HA-Ago2Wt, and A549Ago2-KO/HA-Ago2∆ was analyzed (Figs. 2C and EV2E). Here, CANX is linked to lung carcinoma.