Ago2 is overexpressed in certain types of cancer, such as breast cancer (Casey et al, 2019; Conger et al, 2016), colorectal cancer (Li et al, 2010; Papachristou et al, 2011), ovarian cancer (Vaksman et al, 2012), gastric cancer (Zhang et al, 2013), and glioma (Feng et al, 2014). The gene discussed is AGO2; the disease is cancer.