Many of these Ago2/CAV1-dependent aggressive phenotypes of cancer cells (i.e., invasion (Brandt et al, 2009; Chen et al, 2014; Kressner et al, 2013; Wang et al, 2019), metastasis (Zhang et al, 2022), EMT (Fintha et al, 2013), drug resistance (Zhao et al, 2019), and stemness (Chen et al, 2014), are associated with miR-3613-3p-mediated suppression of SCAI. This evidence concerns the gene AGO2 and cancer.