These cancers also depend on a set of hemoproteins, such as cytochrome c-1 (CYC1), succinate dehydrogenase complex subunit C (SDHC) for cellular respiration, and DGCR8 for microRNA biogenesis (Nguyen et al, 2015), each of which uses heme as a co-factor. The gene discussed is SDHC; the disease is cancer.