Table 3 shows that patients that developed CKD were more likely to be older (P = 0.011), male (P = 0.013), have neurologic involvement (P = 0.015), have diabetes (P = 0.050) and were less likely to have anti-RNP antibodies (P = 0.031). They had significantly higher creatinine levels at diagnosis and a significantly poorer response to treatment (renal response 18% vs 77%, P < 0.001). Here, RNPC3 is linked to chronic kidney disease.