IGFBP7 and cancer: These Gata2-dependent DEGs included Hgf, Pdgfrb, Hdc, Igfbp7, and Lgals3bp, all of which have been implicated in cancer pathogenesis and/or hematopoiesis (53, , , –57); some have previously been described as being regulated by PML::RARA (including Hgf, Pdgfrb, and Hdc) (12, 58).