Our evaluation of this antibody with western blotting did reveal an ability to recognize PML::RARA in APL cells with the bcr1 fusion, but it also recognizes nonspecific proteins of a similar molecular weight in primary human AML cells and human AML cell lines that do not contain the PML::RARA fusion (SI Appendix, Fig. S1C). This evidence concerns the gene PML and acute promyelocytic leukemia.