IGHE and atopic eczema: Also, as a result of the organism's type 1 hypersensitivity response to environmental allergens in atopic dermatitis, a significant increase in IL‐4 and IL‐13 concentrations in addition to intense IgE production has been reported (Chaudhary et al., 2019; Maden et al., 2013; Majewska et al., 2016)