MBOAT7 and metabolic dysfunction-associated steatotic liver disease: In previous independent studies examining lipid alterations in Mboat7-HSKO mice under experimental conditions to elicit NAFLD and fibrosis (i.e., high fat diets or methionine/choline-deficient diets), the global lipidomic alterations in the liver were much more confined to inositol-containing phospholipids and triacylglycerols (Tanaka et al., 2021; Thangapandi et al., 2021).