Using the same process as above, we identified two driver TFs with a significant change in PPR between case and control for the AF-schizophrenia cohort and no significant difference between case and control in the AT-schizophrenia group, SOX11 (FDR 1.73×10–2) and MGA (FDR 9.83×10–3) (Figure 5B; Supplementary file 13). Here, SOX11 is linked to schizophrenia.