As previously reported by Nordström et al,19 the area under the curve for detecting clinically significant prostate cancer was 0.76 (95% CI, 0.72-0.80) for the Stockholm3 risk score and 0.60 (95% CI, 0.54-0.65) for the PSA test, both only for men undergoing systematic biopsy. Here, KLK3 is linked to prostate carcinoma.